On the morning of August 1st, a girl wakes up to find she has lost all her memories before the day. A boy appears in front of her and tells her that he is a spirit named Orion, whose spirited collided with hers and caused her amnesia. He wishes to help her collect her lost memories. One day, she receives a phone call from an unknown man. He says he is her lover. She struggles not to let him notice that she doesn't remember him but...

Amnesia (the anime) is an anime television series adaptation of a Playstation Portable otome game (dating sim game) called Amnesia airing in Winter 2012 - 2013